T Cells Stay FIT During Flu

A less fit flu virus

A team of researchers from the State University of New York at Stony Brook has used a computer-guided approach to engineer live attenuated influenza strains that protect mice from wild-type flu virus.1 The researchers think the strategy could lead to quicker, more efficient ways of producing live attenuated influenza vaccines than the method used to generate strains for the one marketed product...

Stay Professionally Fit, Always

Lymphocytes shrink to stay fit

In response to an infection, proinfl ammatory cytokines stimulate lymphocytes to take up nutrients so that they can proliferate and mount an immune response. Once the infection is cleared, however, cytokine levels decline and the lymphocytes’ nutrient supply is abruptly cut off. Most of the cells quickly die by apoptosis, but a small fraction survive and differentiate into longlived memory cell...

Ratio of CD4+ to CD8+ T-Cells in the Recent Reported Cases of Bird Flu Infection in Asia

Most people can stay fit and healthy into old age

Bruno Vellas tells Fiona Fleck why governments must act now to help older people stay fit and healthy.